Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msp_1069Predicted regulator of aminoacid metabolism; COG2150. (167 aa)    
Predicted Functional Partners:
ribK
Predicted transcriptional regulator; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
   
 0.672
Msp_1063
Predicted RNA-binding protein; Pfam01472, smart00359.
 
     0.654
Msp_0996
Conserved hypothetical protein; Pfam03684; Belongs to the UPF0179 family.
  
   
 0.652
trpE
TrpE; Anthranilate/para-aminobenzoate synthase component I.
     
 0.596
Msp_1146
Partially conserved hypothetical protein; Related to metal-dependent protease; COG1310.
  
     0.586
Msp_1143
Putative transcriptional regulator; COG1395.
  
     0.578
hisB
HisB; Imidazoleglycerol-phosphate dehydratase.
       0.569
Msp_0345
Conserved hypothetical protein; COG1739, pfam01205.
       0.569
trpG
TrpG; Anthranilate/para-aminobenzoate synthase component II.
       0.551
trpC
TrpC; Indole-3-glycerol phosphate synthase.
       0.551
Your Current Organism:
Methanosphaera stadtmanae
NCBI taxonomy Id: 339860
Other names: M. stadtmanae DSM 3091, Methanosphaera stadtmanae ATCC 43021, Methanosphaera stadtmanae DSM 3091, Methanosphaera stadtmanae MCB-3, Methanosphaera stadtmanae str. DSM 3091, Methanosphaera stadtmanae strain DSM 3091
Server load: low (12%) [HD]