STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msp_1069Predicted regulator of aminoacid metabolism; COG2150. (167 aa)    
Predicted Functional Partners:
ribK
Predicted transcriptional regulator; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
   
 0.672
Msp_1063
Predicted RNA-binding protein; Pfam01472, smart00359.
 
     0.658
trpE
TrpE; Anthranilate/para-aminobenzoate synthase component I.
     
 0.617
Msp_0996
Conserved hypothetical protein; Pfam03684; Belongs to the UPF0179 family.
  
   
 0.613
Msp_1146
Partially conserved hypothetical protein; Related to metal-dependent protease; COG1310.
  
     0.586
Msp_1143
Putative transcriptional regulator; COG1395.
  
     0.578
trpG
TrpG; Anthranilate/para-aminobenzoate synthase component II.
       0.553
trpC
TrpC; Indole-3-glycerol phosphate synthase.
       0.553
Msp_1537
Predicted diphthamide synthase, subunit DPH2; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.
  
     0.528
trpF
TrpF; N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
       0.527
Your Current Organism:
Methanosphaera stadtmanae
NCBI taxonomy Id: 339860
Other names: M. stadtmanae DSM 3091, Methanosphaera stadtmanae ATCC 43021, Methanosphaera stadtmanae DSM 3091, Methanosphaera stadtmanae MCB-3, Methanosphaera stadtmanae str. DSM 3091, Methanosphaera stadtmanae strain DSM 3091
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