STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A3306_00260Transposase; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)    
Predicted Functional Partners:
ARD85870.1
Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.976
ARD86388.1
Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.976
ARD86835.1
Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.976
ARD85736.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
      0.864
gabD
NAD-dependent succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
  
 
 0.785
A3306_00275
Transposase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
      0.688
ARD86385.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.680
ARD86692.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.672
gltA
Citrate (Si)-synthase; Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cit [...]
   
  
 0.605
sdhA
Fumarate reductase (quinol) flavoprotein subunit; Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD- [...]
  
  
 0.563
Your Current Organism:
Rickettsia bellii
NCBI taxonomy Id: 33990
Other names: R. bellii, RML 369-C, strain 369L42-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.