STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (502 aa)    
Predicted Functional Partners:
ARD85816.1
Serine peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S1C family.
  
  
 0.878
ARD86089.1
Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.833
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.825
ARD86330.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.777
sppA
Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.705
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
  0.594
ARD86613.1
Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.526
ARD86332.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.518
groEL
Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.518
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
  
    0.517
Your Current Organism:
Rickettsia bellii
NCBI taxonomy Id: 33990
Other names: R. bellii, RML 369-C, strain 369L42-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.