KOEU_24840 protein (Komagataeibacter europaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KOEU_24840

Hypothetical protein. (137 aa)

Predicted Functional Partners:

traG2

0.946

KOEU_12660

0.782

KOEU_12740

0.782

KOEU_24790

0.782

KOEU_24880

0.782

KOEU_24900

0.781

KOEU_12640

0.780

KOEU_12790

0.779

KOEU_12810

0.779

KOEU_24750

0.779

Your Current Organism:

Komagataeibacter europaeus

NCBI taxonomy Id: 33995
Other names: ATCC 51845, Acetobacter europaeus, DSM 6160, Gluconacetobacter europaeus, K. europaeus, LMG 18890, LMG:18890, strain DES 11

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KOEU_12640	KOEU_12660	KOEU_12640	KOEU_12660	Hypothetical protein.	Type IV secretory pathway, VirB3-like protein.	0.946
KOEU_12640	KOEU_12740	KOEU_12640	KOEU_12740	Hypothetical protein.	Hypothetical protein.	0.774
KOEU_12640	KOEU_12790	KOEU_12640	KOEU_12790	Hypothetical protein.	Hypothetical protein.	0.748
KOEU_12640	KOEU_12810	KOEU_12640	KOEU_12810	Hypothetical protein.	Hypothetical protein.	0.763
KOEU_12640	KOEU_24750	KOEU_12640	KOEU_24750	Hypothetical protein.	Hypothetical protein.	0.738
KOEU_12640	KOEU_24790	KOEU_12640	KOEU_24790	Hypothetical protein.	Hypothetical protein.	0.779
KOEU_12640	KOEU_24840	KOEU_12640	KOEU_24840	Hypothetical protein.	Hypothetical protein.	0.780
KOEU_12640	KOEU_24880	KOEU_12640	KOEU_24880	Hypothetical protein.	Type IV secretory pathway, VirB3-like protein.	0.794
KOEU_12640	traG2	KOEU_12640	KOEU_24830	Hypothetical protein.	Conjugal transfer protein TraG.	0.777
KOEU_12660	KOEU_12640	KOEU_12660	KOEU_12640	Type IV secretory pathway, VirB3-like protein.	Hypothetical protein.	0.946
KOEU_12660	KOEU_12740	KOEU_12660	KOEU_12740	Type IV secretory pathway, VirB3-like protein.	Hypothetical protein.	0.764
KOEU_12660	KOEU_12790	KOEU_12660	KOEU_12790	Type IV secretory pathway, VirB3-like protein.	Hypothetical protein.	0.669
KOEU_12660	KOEU_12810	KOEU_12660	KOEU_12810	Type IV secretory pathway, VirB3-like protein.	Hypothetical protein.	0.732
KOEU_12660	KOEU_24750	KOEU_12660	KOEU_24750	Type IV secretory pathway, VirB3-like protein.	Hypothetical protein.	0.632
KOEU_12660	KOEU_24790	KOEU_12660	KOEU_24790	Type IV secretory pathway, VirB3-like protein.	Hypothetical protein.	0.772
KOEU_12660	KOEU_24840	KOEU_12660	KOEU_24840	Type IV secretory pathway, VirB3-like protein.	Hypothetical protein.	0.782
KOEU_12660	KOEU_24900	KOEU_12660	KOEU_24900	Type IV secretory pathway, VirB3-like protein.	Hypothetical protein.	0.794
KOEU_12660	traG2	KOEU_12660	KOEU_24830	Type IV secretory pathway, VirB3-like protein.	Conjugal transfer protein TraG.	0.774
KOEU_12740	KOEU_12640	KOEU_12740	KOEU_12640	Hypothetical protein.	Hypothetical protein.	0.774
KOEU_12740	KOEU_12660	KOEU_12740	KOEU_12660	Hypothetical protein.	Type IV secretory pathway, VirB3-like protein.	0.764

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.879

expected number of edges:

42

PPI enrichment p-value:

0.995

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006457

Protein folding

5 of 22

1.87

2.29

9.82e-06

GO:0009408

Response to heat

3 of 10

1.99

1.23

0.0041

GO:0051603

Proteolysis involved in protein catabolic process

2 of 4

2.21

0.79

0.0344

GO:0050821

Protein stabilization

2 of 4

2.21

0.79

0.0344

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005515

Protein binding

6 of 48

1.61

2.14

2.81e-06

GO:0051082

Unfolded protein binding

3 of 10

1.99

1.36

0.0022

GO:0140662

ATP-dependent protein folding chaperone

2 of 4

2.21

0.88

0.0237

GO:0004176

ATP-dependent peptidase activity

2 of 4

2.21

0.88

0.0237

GO:0140657

ATP-dependent activity

5 of 137

1.08

0.74

0.0085

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 1235

0.46

0.38

0.0011

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:36350115

(2022) Shared properties of gene transfer agent and core genes revealed by comparative genomics of Alphaproteobacteria.

2 of 3

2.34

1.12

0.0086

PMID:32093084

(2020) Adaptation to Photooxidative Stress: Common and Special Strategies of the Alphaproteobacteria Rhodobacter sphaeroides and Rhodobacter capsulatus.

3 of 26

1.58

0.98

0.0086

PMID:33780465

(2021) Adaptation of Dinoroseobacter shibae to oxidative stress and the specific role of RirA.

3 of 51

1.28

0.75

0.0186

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:378

Chaperone, and Cellular response to heat

10 of 16

2.31

7.89

5.09e-19

CL:381

Stress response, and Protein folding chaperone

8 of 10

2.42

6.85

2.99e-15

CL:384

Protein folding chaperone, and Chaperone binding

4 of 5

2.42

3.15

8.49e-07

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1236975

Antigen processing-Cross presentation

3 of 4

2.39

2.58

1.19e-05

MAP-983169

Class I MHC mediated antigen processing & presentation

3 of 6

2.21

2.47

1.42e-05

MAP-1280218

Adaptive Immune System

3 of 6

2.21

2.47

1.42e-05

MAP-168256

Immune System

3 of 27

1.56

1.48

0.00033

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009368

Endopeptidase Clp complex

2 of 3

2.34

0.86

0.0262

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0346

Stress response

8 of 16

2.21

5.89

3.95e-14

KW-0143

Chaperone

5 of 23

1.85

2.62

9.96e-07

KW-0720

Serine protease

2 of 5

2.12

1.09

0.0088

KW-0645

Protease

3 of 34

1.46

0.93

0.0088

KW-0963

Cytoplasm

7 of 252

0.96

0.89

0.00018

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00011

Hsp20/alpha crystallin family

3 of 3

2.51

1.95

0.00024

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR008978

HSP20-like chaperone

3 of 3

2.51

1.73

0.00064

IPR002068

Alpha crystallin/Hsp20 domain

3 of 3

2.51

1.73

0.00064

IPR037913

Small heat shock protein IbpA/IbpB, ACD domain

2 of 2

2.51

0.88

0.0255

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Textmining

Cooccurrence

Experiments

Fusion

Databases

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About