node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KOEU_31610 | metE4 | KOEU_31610 | KOEU_31600 | Transposase DDE domain protein. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.580 |
MetF | ahcY | KOEU_08490 | KOEU_16430 | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.465 |
MetF | metC | KOEU_08490 | KOEU_26190 | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | Cystathionine beta-lyase. | 0.872 |
MetF | metE4 | KOEU_08490 | KOEU_31600 | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.832 |
MetF | metH | KOEU_08490 | KOEU_22250 | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.996 |
MetF | metK | KOEU_08490 | KOEU_08890 | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | S-adenosylmethionine synthase; Belongs to the AdoMet synthase family. | 0.876 |
MetF | metZ | KOEU_08490 | KOEU_15460 | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.854 |
ahcY | MetF | KOEU_16430 | KOEU_08490 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | 0.465 |
ahcY | metC | KOEU_16430 | KOEU_26190 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Cystathionine beta-lyase. | 0.921 |
ahcY | metE4 | KOEU_16430 | KOEU_31600 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.543 |
ahcY | metH | KOEU_16430 | KOEU_22250 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.961 |
ahcY | metK | KOEU_16430 | KOEU_08890 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | S-adenosylmethionine synthase; Belongs to the AdoMet synthase family. | 0.892 |
ahcY | metZ | KOEU_16430 | KOEU_15460 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.938 |
cynR7 | metE4 | KOEU_29760 | KOEU_31600 | HTH-type transcriptional regulator CynR; Belongs to the LysR transcriptional regulatory family. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.497 |
metC | MetF | KOEU_26190 | KOEU_08490 | Cystathionine beta-lyase. | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | 0.872 |
metC | ahcY | KOEU_26190 | KOEU_16430 | Cystathionine beta-lyase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.921 |
metC | metE4 | KOEU_26190 | KOEU_31600 | Cystathionine beta-lyase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.419 |
metC | metH | KOEU_26190 | KOEU_22250 | Cystathionine beta-lyase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.981 |
metC | metK | KOEU_26190 | KOEU_08890 | Cystathionine beta-lyase. | S-adenosylmethionine synthase; Belongs to the AdoMet synthase family. | 0.412 |
metC | metZ | KOEU_26190 | KOEU_15460 | Cystathionine beta-lyase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.926 |