STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metE45-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (436 aa)    
Predicted Functional Partners:
MetF
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
  
 
 0.832
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.666
metK
S-adenosylmethionine synthase; Belongs to the AdoMet synthase family.
  
 
 0.608
KOEU_31610
Transposase DDE domain protein.
       0.580
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
  
 0.543
cynR7
HTH-type transcriptional regulator CynR; Belongs to the LysR transcriptional regulatory family.
 
    0.497
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
  
 0.419
metC
Cystathionine beta-lyase.
  
  
 0.419
Your Current Organism:
Komagataeibacter europaeus
NCBI taxonomy Id: 33995
Other names: ATCC 51845, Acetobacter europaeus, DSM 6160, Gluconacetobacter europaeus, K. europaeus, LMG 18890, LMG:18890, strain DES 11
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