node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEN58640.1 | asd | SAMN04489859_101056 | SAMN04489859_102253 | Glutamate synthase (NADPH) large subunit. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.757 |
SEN58640.1 | carB | SAMN04489859_101056 | SAMN04489859_101279 | Glutamate synthase (NADPH) large subunit. | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.982 |
SEN58640.1 | dapF | SAMN04489859_101056 | SAMN04489859_103039 | Glutamate synthase (NADPH) large subunit. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.950 |
SEN58640.1 | murE | SAMN04489859_101056 | SAMN04489859_10518 | Glutamate synthase (NADPH) large subunit. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.519 |
SEO02862.1 | dapE | SAMN04489859_102948 | SAMN04489859_102841 | Acetylornithine deacetylase. | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.839 |
SEO02862.1 | dapF | SAMN04489859_102948 | SAMN04489859_103039 | Acetylornithine deacetylase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.774 |
SEO02862.1 | lysA | SAMN04489859_102948 | SAMN04489859_10047 | Acetylornithine deacetylase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.475 |
SEO04099.1 | dapF | SAMN04489859_103038 | SAMN04489859_103039 | Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.904 |
asd | SEN58640.1 | SAMN04489859_102253 | SAMN04489859_101056 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Glutamate synthase (NADPH) large subunit. | 0.757 |
asd | carB | SAMN04489859_102253 | SAMN04489859_101279 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.403 |
asd | dapF | SAMN04489859_102253 | SAMN04489859_103039 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.877 |
asd | lysA | SAMN04489859_102253 | SAMN04489859_10047 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.789 |
carB | SEN58640.1 | SAMN04489859_101279 | SAMN04489859_101056 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Glutamate synthase (NADPH) large subunit. | 0.982 |
carB | asd | SAMN04489859_101279 | SAMN04489859_102253 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.403 |
carB | dapF | SAMN04489859_101279 | SAMN04489859_103039 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.957 |
carB | lysA | SAMN04489859_101279 | SAMN04489859_10047 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.529 |
carB | murF | SAMN04489859_101279 | SAMN04489859_10517 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.416 |
dapE | SEO02862.1 | SAMN04489859_102841 | SAMN04489859_102948 | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Acetylornithine deacetylase. | 0.839 |
dapE | dapF | SAMN04489859_102841 | SAMN04489859_103039 | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.968 |
dapE | lysA | SAMN04489859_102841 | SAMN04489859_10047 | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.550 |