STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobLPrecorrin-6Y C(5,15)-methyltransferase [decarboxylating]. (404 aa)    
Predicted Functional Partners:
cobH
Precorrin-8X methylmutase.
 
 
 0.999
cobJ
Precorrin-3B C(17)-methyltransferase.
 
 
 0.999
cobM
Precorrin-4 C(11)-methyltransferase.
 
 0.999
cbiD
cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
 0.998
cobI
Precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.996
cobK
Precorrin-6A reductase.
 
 
 0.994
cbiX
Sirohydrochlorin cobaltochelatase.
 
  
 0.986
cobN
Aerobic cobaltochelatase subunit CobN.
 
  
 0.961
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
 
 0.950
cobB_2
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.925
Your Current Organism:
Thalassobius mediterraneus
NCBI taxonomy Id: 340021
Other names: CCUG 49438, CECT 5383, CIP 108400, DSM 16398, T. mediterraneus, Thalassobius mediterraneus Arahal et al. 2005, strain XSM19
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.