STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUH83004.1Hypothetical protein. (610 aa)    
Predicted Functional Partners:
prsD_1
Type I secretion system ATP-binding protein PrsD.
 
     0.816
prsE_1
Type I secretion system membrane fusion protein PrsE.
 
     0.741
luxQ_2
Autoinducer 2 sensor kinase/phosphatase LuxQ.
  
 0.669
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.604
parE
DNA topoisomerase 4 subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
    
 
 0.604
bcsA_1
Cellulose synthase catalytic subunit [UDP-forming].
  
    0.550
CUH83003.1
Hypothetical protein.
       0.547
CUH83273.1
Beta-mannanase; Belongs to the glycosyl hydrolase 26 family.
  
     0.513
ttuE
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.477
CUH86025.1
Putative transcription regulator, contains HTH domain (MarR family).
  
     0.423
Your Current Organism:
Thalassobius mediterraneus
NCBI taxonomy Id: 340021
Other names: CCUG 49438, CECT 5383, CIP 108400, DSM 16398, T. mediterraneus, Thalassobius mediterraneus Arahal et al. 2005, strain XSM19
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.