STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pucM5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (118 aa)    
Predicted Functional Partners:
uao
Uric acid degradation bifunctional protein.
 
 0.999
CUH85032.1
Putative membrane protein.
 
  
 0.919
allA
Ureidoglycolate hydrolase.
 
    0.851
xdhA
Xanthine dehydrogenase molybdenum-binding subunit.
 
  
 0.802
guaD_2
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
   
 0.726
guaD_1
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
   
 0.724
uacT
Uric acid transporter UacT.
 
  
 0.711
pucE
Putative xanthine dehydrogenase subunit E.
 
     0.705
yedZ
Flavocytochrome YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the [...]
   
    0.694
CUH84285.1
Xanthine dehydrogenase accessory protein XdhC.
 
     0.655
Your Current Organism:
Thalassobius mediterraneus
NCBI taxonomy Id: 340021
Other names: CCUG 49438, CECT 5383, CIP 108400, DSM 16398, T. mediterraneus, Thalassobius mediterraneus Arahal et al. 2005, strain XSM19
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