node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MenF | SFH25383.1 | SAMN04488021_12913 | SAMN04488021_10495 | Isochorismate synthase. | Chorismate mutase. | 0.872 |
MenF | TrpG | SAMN04488021_12913 | SAMN04488021_101123 | Isochorismate synthase. | Anthranilate synthase, component II. | 0.930 |
MenF | aroC | SAMN04488021_12913 | SAMN04488021_10676 | Isochorismate synthase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.875 |
MenF | trpA | SAMN04488021_12913 | SAMN04488021_11417 | Isochorismate synthase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.557 |
MenF | trpB | SAMN04488021_12913 | SAMN04488021_11560 | Isochorismate synthase. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.530 |
MenF | trpC | SAMN04488021_12913 | SAMN04488021_101120 | Isochorismate synthase. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.568 |
MenF | trpD | SAMN04488021_12913 | SAMN04488021_101122 | Isochorismate synthase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.616 |
MenF | trpE | SAMN04488021_12913 | SAMN04488021_101127 | Isochorismate synthase. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.861 |
MenF | trpF | SAMN04488021_12913 | SAMN04488021_11558 | Isochorismate synthase. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.542 |
SFH12537.1 | SFH25383.1 | SAMN04488021_101315 | SAMN04488021_10495 | Aminodeoxychorismate synthase, subunit I. | Chorismate mutase. | 0.826 |
SFH12537.1 | TrpG | SAMN04488021_101315 | SAMN04488021_101123 | Aminodeoxychorismate synthase, subunit I. | Anthranilate synthase, component II. | 0.999 |
SFH12537.1 | aroC | SAMN04488021_101315 | SAMN04488021_10676 | Aminodeoxychorismate synthase, subunit I. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.943 |
SFH12537.1 | trpA | SAMN04488021_101315 | SAMN04488021_11417 | Aminodeoxychorismate synthase, subunit I. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.936 |
SFH12537.1 | trpB | SAMN04488021_101315 | SAMN04488021_11560 | Aminodeoxychorismate synthase, subunit I. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.931 |
SFH12537.1 | trpC | SAMN04488021_101315 | SAMN04488021_101120 | Aminodeoxychorismate synthase, subunit I. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.986 |
SFH12537.1 | trpD | SAMN04488021_101315 | SAMN04488021_101122 | Aminodeoxychorismate synthase, subunit I. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.988 |
SFH12537.1 | trpE | SAMN04488021_101315 | SAMN04488021_101127 | Aminodeoxychorismate synthase, subunit I. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.839 |
SFH12537.1 | trpF | SAMN04488021_101315 | SAMN04488021_11558 | Aminodeoxychorismate synthase, subunit I. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.942 |
SFH25383.1 | MenF | SAMN04488021_10495 | SAMN04488021_12913 | Chorismate mutase. | Isochorismate synthase. | 0.872 |
SFH25383.1 | SFH12537.1 | SAMN04488021_10495 | SAMN04488021_101315 | Chorismate mutase. | Aminodeoxychorismate synthase, subunit I. | 0.826 |