Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lacZBeta-galactosidase; PFAM: glycoside hydrolase family 2, immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2, TIM barrel; glycoside hydrolase family 2, sugar binding. (743 aa)    
Predicted Functional Partners:
ABY94274.1
PFAM: glycoside hydrolase, clan GH-D.
 
 
 0.991
ABY95804.1
PFAM: glycoside hydrolase, family 5; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
 
  
  0.916
ABY94242.1
TIGRFAM: putative glucokinase, ROK family; PFAM: ROK family protein; ATPase, BadF/BadG/BcrA/BcrD type.
    
 0.906
ABY95777.1
TIGRFAM: putative glucokinase, ROK family; PFAM: ROK family protein.
    
 0.906
xylA
TIGRFAM: xylose isomerase; PFAM: Xylose isomerase domain protein TIM barrel; Belongs to the xylose isomerase family.
 
  
 0.847
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
  
 0.745
ABY94272.1
PFAM: binding-protein-dependent transport systems inner membrane component.
  
    0.719
ABY94273.1
PFAM: binding-protein-dependent transport systems inner membrane component.
       0.714
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
    
 
 0.659
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.646
Your Current Organism:
Thermoanaerobacter pseudethanolicus
NCBI taxonomy Id: 340099
Other names: Clostridium thermohydrosulfuricum 39E, T. pseudethanolicus ATCC 33223, Thermoanaerobacter ethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus 39E, Thermoanaerobacter pseudethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus str. ATCC 33223, Thermoanaerobacter pseudethanolicus strain ATCC 33223
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.