Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABY94400.1PFAM: protein of unknown function DUF633. (234 aa)    
Predicted Functional Partners:
ABY94401.1
PFAM: protein of unknown function DUF34; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
 0.990
ABY94708.1
PFAM: protein of unknown function DUF965; Belongs to the UPF0297 family.
  
     0.723
ABY94984.1
PFAM: protein of unknown function DUF814; Fibronectin-binding A domain protein.
 
     0.619
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
  
     0.615
ABY95012.1
Transcriptional regulator with CBS sensor domain, DeoR family; PFAM: CBS domain containing protein; regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein.
 
     0.576
ABY95897.1
PFAM: protein of unknown function DUF951.
  
     0.555
ABY94676.1
PFAM: Radical SAM domain protein.
  
     0.548
addA
UvrD-like DNA helicase, C terminal; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily.
 
     0.548
ABY94932.1
Putative helix-turn-helix protein, YlxM/p13 family protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.546
sigA
RNA polymerase, sigma 70 subunit, RpoD family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
       0.532
Your Current Organism:
Thermoanaerobacter pseudethanolicus
NCBI taxonomy Id: 340099
Other names: Clostridium thermohydrosulfuricum 39E, T. pseudethanolicus ATCC 33223, Thermoanaerobacter ethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus 39E, Thermoanaerobacter pseudethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus str. ATCC 33223, Thermoanaerobacter pseudethanolicus strain ATCC 33223
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