node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABY94396.1 | ABY94673.1 | Teth39_0736 | Teth39_1018 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | 0.941 |
ABY94396.1 | ABY95913.1 | Teth39_0736 | Teth39_2292 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | PFAM: 60 kDa inner membrane insertion protein. | 0.976 |
ABY94396.1 | ffh | Teth39_0736 | Teth39_1277 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.972 |
ABY94396.1 | ftsY | Teth39_0736 | Teth39_1279 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.981 |
ABY94396.1 | secA | Teth39_0736 | Teth39_1755 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.982 |
ABY94396.1 | secD | Teth39_0736 | Teth39_1023 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.897 |
ABY94396.1 | secE | Teth39_0736 | Teth39_0360 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.995 |
ABY94396.1 | secY | Teth39_0736 | Teth39_0393 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.991 |
ABY94673.1 | ABY94396.1 | Teth39_1018 | Teth39_0736 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.941 |
ABY94673.1 | ABY95913.1 | Teth39_1018 | Teth39_2292 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | PFAM: 60 kDa inner membrane insertion protein. | 0.934 |
ABY94673.1 | ffh | Teth39_1018 | Teth39_1277 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.933 |
ABY94673.1 | ftsY | Teth39_1018 | Teth39_1279 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.942 |
ABY94673.1 | queA | Teth39_1018 | Teth39_1016 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | S-adenosylmethionine--tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.867 |
ABY94673.1 | secA | Teth39_1018 | Teth39_1755 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.936 |
ABY94673.1 | secD | Teth39_1018 | Teth39_1023 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.825 |
ABY94673.1 | secE | Teth39_1018 | Teth39_0360 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.958 |
ABY94673.1 | secY | Teth39_1018 | Teth39_0393 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.948 |
ABY94673.1 | tgt | Teth39_1018 | Teth39_1017 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...] | 0.908 |
ABY95913.1 | ABY94396.1 | Teth39_2292 | Teth39_0736 | PFAM: 60 kDa inner membrane insertion protein. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.976 |
ABY95913.1 | ABY94673.1 | Teth39_2292 | Teth39_1018 | PFAM: 60 kDa inner membrane insertion protein. | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | 0.934 |