Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABY94777.1RNA polymerase, sigma 28 subunit, FliA/WhiG family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. (246 aa)    
Predicted Functional Partners:
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.991
ABY94775.1
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; Anti-sigma factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family.
 
  
 0.969
ABY94779.1
PFAM: SpoVA protein.
 
     0.856
ABY94780.1
PFAM: Stage V sporulation AD family protein.
 
     0.852
ABY94781.1
PFAM: SpoVA protein.
 
     0.851
ABY95114.1
Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region, ATPase domain protein domain protein.
  
 
 0.791
ABY94763.1
PFAM: peptidase S55, SpoIVB.
 
   
 0.735
ABY94764.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
 
   
 0.726
ABY94499.1
Hypothetical protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.720
ABY95718.1
Sporulation transcriptional regulator SpoIIID; TIGRFAM: regulatory protein, DeoR.
  
     0.707
Your Current Organism:
Thermoanaerobacter pseudethanolicus
NCBI taxonomy Id: 340099
Other names: Clostridium thermohydrosulfuricum 39E, T. pseudethanolicus ATCC 33223, Thermoanaerobacter ethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus 39E, Thermoanaerobacter pseudethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus str. ATCC 33223, Thermoanaerobacter pseudethanolicus strain ATCC 33223
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