Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABY95780.1PFAM: SirA family protein; Belongs to the sulfur carrier protein TusA family. (75 aa)    
Predicted Functional Partners:
ABY95779.1
PFAM: protein of unknown function DUF395, YeeE/YedE.
 
  
 0.961
ABY95781.1
PFAM: protein of unknown function DUF395, YeeE/YedE.
 
  
 0.957
ABY95778.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; HI0933 family protein.
 
   
 0.863
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 
 0.714
ABY94454.1
PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II.
   
 
 0.714
ABY95782.1
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
 
   
 0.569
ABY95478.1
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
   
 
 0.401
ABY94502.1
TIGRFAM: putative CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; 2-hydroxyglutaryl-CoA dehydratase, D-component.
  
    0.400
Your Current Organism:
Thermoanaerobacter pseudethanolicus
NCBI taxonomy Id: 340099
Other names: Clostridium thermohydrosulfuricum 39E, T. pseudethanolicus ATCC 33223, Thermoanaerobacter ethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus 39E, Thermoanaerobacter pseudethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus str. ATCC 33223, Thermoanaerobacter pseudethanolicus strain ATCC 33223
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