Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABY95823.1TIGRFAM: PAS sensor protein; PFAM: histidine kinase, HAMP region domain protein; metal-dependent phosphohydrolase, HD sub domain; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; HDOD; SMART: PAS domain containing protein; metal-dependent phosphohydrolase, HD region. (632 aa)    
Predicted Functional Partners:
ABY93999.1
Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein.
 
 0.988
ABY95029.1
TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; SMART: PAS domain containing protein.
 
 0.933
ABY93952.1
Diguanylate phosphodiesterase; PFAM: EAL domain protein.
 
 
 0.877
ABY94419.1
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver.
 
 0.773
ABY94437.1
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2.
 
 
 0.761
ABY95739.1
PFAM: response regulator receiver.
 
 
 0.736
ABY94665.1
PFAM: CheW domain protein.
  
 
 0.711
ABY94885.1
PFAM: CheW domain protein.
  
 
 0.711
ABY94886.1
CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; P2 response regulator binding domain protein.
  
  
 0.679
ABY93838.1
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein.
  
 
 0.674
Your Current Organism:
Thermoanaerobacter pseudethanolicus
NCBI taxonomy Id: 340099
Other names: Clostridium thermohydrosulfuricum 39E, T. pseudethanolicus ATCC 33223, Thermoanaerobacter ethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus 39E, Thermoanaerobacter pseudethanolicus ATCC 33223, Thermoanaerobacter pseudethanolicus str. ATCC 33223, Thermoanaerobacter pseudethanolicus strain ATCC 33223
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