Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pars_0791KEGG: pai:PAE2187 hypothetical protein. (204 aa)    
Predicted Functional Partners:
Pars_0792
Hypothetical protein; KEGG: pis:Pisl_0810 family 453, possible regulatory protein.
       0.722
Pars_0793
TIGRFAM: putative hydroxymethylglutaryl-CoA synthase; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; KEGG: pai:PAE2185 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. UPF0219 family.
       0.706
Pars_0794
PFAM: protein of unknown function DUF35; KEGG: pai:PAE2184 conserved protein associated with acetyl-CoA C-acyltransferase.
       0.706
Pars_0795
KEGG: pai:PAE2183 acetyl-CoA C-acyltransferase.
       0.616
Pars_0796
KEGG: pai:PAE2182 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase); TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase; PFAM: hydroxymethylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
       0.457
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.