STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pars_1913PFAM: metallophosphoesterase; KEGG: pai:PAE2243 hypothetical protein. (260 aa)    
Predicted Functional Partners:
Pars_1912
KEGG: pai:PAE2244 hypothetical protein.
       0.726
Pars_1750
KEGG: pai:PAE3336 putative nucleotide binding protein.
  
     0.648
pfdB
Prefoldin, beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
     0.640
ribK
CTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.625
Pars_2337
FMN adenylyltransferase; TIGRFAM: cytidyltransferase-related domain; PFAM: cytidylyltransferase; KEGG: pai:PAE0683 cytidyltransferase.
       0.610
rpl21e
PFAM: ribosomal protein L21e; KEGG: pis:Pisl_0578 ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
  
     0.576
rpl18e
PFAM: ribosomal protein L15; KEGG: pis:Pisl_0696 ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL18 family.
  
     0.573
dnaG
TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
     0.563
Pars_0037
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: pai:PAE0783 conserved helix-turn-helix protein.
  
     0.561
priL
DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
  
     0.557
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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