Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pars_1920Predicted aconitase subunit 1; PFAM: protein of unknown function DUF521; KEGG: pai:PAE2233 hypothetical protein. (373 aa)    
Predicted Functional Partners:
Pars_1919
KEGG: pai:PAE2234 hypothetical protein.
 
 
 0.999
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
 
  
  0.927
Pars_1921
TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: pai:PAE2232 hypothetical protein.
 
     0.868
albA
Nucleoid protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family.
 
     0.575
tmk
PFAM: thymidylate kinase; KEGG: pis:Pisl_1194 dTMP kinase.
       0.529
Pars_1371
KEGG: pis:Pisl_1337 protein of unknown function DUF650.
  
     0.466
Pars_1923
Hypothetical protein.
       0.464
rpl31e
PFAM: Ribosomal protein L31e; KEGG: pai:PAE3095 ribosomal protein L31; Belongs to the eukaryotic ribosomal protein eL31 family.
  
     0.456
Pars_2292
PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: pai:PAE0632 hypothetical protein.
 
     0.437
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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