Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pars_1983KEGG: pai:PAE1635 hypothetical protein. (330 aa)    
Predicted Functional Partners:
Pars_1982
KEGG: pai:PAE1636 hypothetical protein.
 
     0.923
Pars_1984
PFAM: putative RNA methylase; KEGG: pai:PAE1634 hypothetical protein.
       0.906
Pars_1981
SMART: helix-turn-helix domain protein; KEGG: pai:PAE1638 putative transcriptional regulator.
 
     0.807
Pars_1542
PFAM: protein of unknown function DUF115; KEGG: pai:PAE2328 hypothetical protein.
 
     0.713
ribK
CTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.640
priL
DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
 
     0.635
tiaS
tRNA(Ile2) 2-agmatinylcytidine synthetase; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
     0.614
Pars_1926
Phosphate uptake regulator, PhoU; TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; PhoU family protein; KEGG: pai:PAE2220 hypothetical protein.
  
     0.602
pfdB
Prefoldin, beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
     0.592
Pars_1913
PFAM: metallophosphoesterase; KEGG: pai:PAE2243 hypothetical protein.
 
     0.556
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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