Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pars_1985PFAM: Protein of unknown function DUF54; KEGG: pai:PAE1632 conserved hypothetical protein; Belongs to the UPF0201 family. (143 aa)    
Predicted Functional Partners:
Pars_1986
KEGG: pai:PAE1629 adenylate kinase, conjectural.
 
    0.921
trm1
N(2),N(2)-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
       0.781
Pars_1988
PFAM: helix-turn-helix domain protein; KEGG: pai:PAE1627 putative transcriptional regulator.
       0.759
Pars_1989
PFAM: PUA domain containing protein; KEGG: pai:PAE1626 PUA domain protein.
 
     0.628
Pars_1990
KEGG: pai:PAE1625 putative serine/threonine protein kinase.
 
     0.628
Pars_2002
Pantothenate kinase; KEGG: pai:PAE3407 hypothetical protein.
  
     0.624
Pars_2262
PFAM: Protein of unknown function DUF1297; Protein of unknown function DUF1246; KEGG: pis:Pisl_0095 protein of unknown function DUF1297.
  
     0.591
Pars_1931
PFAM: Protein of unknown function DUF54; KEGG: pai:PAE2213 hypothetical protein.
  
     0.573
Pars_2001
Pantothenate synthetase; PFAM: Protein of unknown function DUF137; KEGG: pai:PAE3406 hypothetical protein.
 
   
 0.567
purP
Protein of unknown function DUF1297; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. Belongs to the phosphohexose mutase family.
  
     0.567
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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