Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pars_1990KEGG: pai:PAE1625 putative serine/threonine protein kinase. (224 aa)    
Predicted Functional Partners:
Pars_1985
PFAM: Protein of unknown function DUF54; KEGG: pai:PAE1632 conserved hypothetical protein; Belongs to the UPF0201 family.
 
     0.628
Pars_2163
PFAM: protein of unknown function DUF343; KEGG: pai:PAE0284 hypothetical protein.
  
     0.621
cca
tRNA adenylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
     
 0.599
Pars_1991
PFAM: Sjogrens syndrome scleroderma autoantigen 1; KEGG: pai:PAE1624 hypothetical protein.
       0.587
endA
tRNA intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
 
     0.540
Pars_1311
PFAM: THUMP domain protein; KEGG: pai:PAE2935 hypothetical protein.
  
     0.539
Pars_1741
2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
       0.537
Pars_1897
KEGG: pis:Pisl_0913 LPXTG-motif cell wall anchor domain.
  
     0.526
Pars_1986
KEGG: pai:PAE1629 adenylate kinase, conjectural.
       0.519
Pars_1318
KEGG: pis:Pisl_0347 conserved hypothetical protein.
  
     0.516
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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