STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pars_2000PFAM: thioesterase superfamily protein; KEGG: pai:PAE3404 acyl coenzyme A thioester hydrolase. (314 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
    0.653
Pars_2001
Pantothenate synthetase; PFAM: Protein of unknown function DUF137; KEGG: pai:PAE3406 hypothetical protein.
       0.562
Pars_1843
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: pai:PAE1650 enoyl-CoA hydratase, probable.
 
 
 
 0.555
Pars_0534
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pai:PAE2687 alcohol dehydrogenase (zinc).
 
   
 0.485
Pars_0305
SMART: phospholipase D/Transphosphatidylase; KEGG: pai:PAE1226 DNA endonuclease, conjectural.
 
   
 0.478
Pars_0453
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: pai:PAE1383 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase.
  
  
 0.431
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.