STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (264 aa)    
Predicted Functional Partners:
Pars_2003
Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
 
  
 0.987
ilvE
Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.932
ilvD
KEGG: pai:PAE0615 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
    
 0.929
Pars_0404
KEGG: pis:Pisl_1381 aspartate 1-decarboxylase.
  
  
 0.909
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.881
Pars_2005
Hypothetical protein.
       0.773
Pars_2002
Pantothenate kinase; KEGG: pai:PAE3407 hypothetical protein.
     
 0.726
Pars_0203
Phosphopantothenate-cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein; KEGG: pis:Pisl_1313 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase.
 
   
 0.619
Pars_2001
Pantothenate synthetase; PFAM: Protein of unknown function DUF137; KEGG: pai:PAE3406 hypothetical protein.
     
 0.536
Pars_1934
KEGG: pai:PAE2210 hypothetical protein.
       0.503
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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