STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pars_2011Amino acid ABC transporter substrate-binding protein, PAAT family; PFAM: extracellular solute-binding protein, family 3; KEGG: pai:PAE2096 bacterial extracellular solute-binding proteins, family 3; TC 3.A.1.3.-. (282 aa)    
Predicted Functional Partners:
Pars_2068
TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pai:PAE2000 glutamine transport system permease protein, putative; TC 3.A.1.3.-.
 
 0.990
Pars_2069
Amino acid ABC transporter ATP-binding protein, PAAT family; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pai:PAE2001 glutamine transport ATP-binding; TC 3.A.1.3.-.
 
 
 0.906
rps14
SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles.
  
    0.700
Pars_2012
D-proline dehydrogenase; PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE2095 conserved within P.aerophilum.
  
  
 0.624
Pars_2013
PFAM: GCN5-related N-acetyltransferase; KEGG: sto:ST2612 hypothetical protein.
       0.564
Pars_0969
PFAM: argininosuccinate synthase; KEGG: pai:PAE2884 argininosuccinate synthase.
  
  
 0.492
argH
PFAM: fumarate lyase; KEGG: pai:PAE2887 argininosuccinate lyase.
  
  
 0.470
aroD
3-dehydroquinate dehydratase / chorismate mutase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
  
  
 0.468
rps8
SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
  
    0.407
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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