STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pars_2012D-proline dehydrogenase; PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE2095 conserved within P.aerophilum. (365 aa)    
Predicted Functional Partners:
Pars_2013
PFAM: GCN5-related N-acetyltransferase; KEGG: sto:ST2612 hypothetical protein.
 
     0.817
Pars_2164
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE1841 hypothetical protein.
 
 
 0.772
Pars_2011
Amino acid ABC transporter substrate-binding protein, PAAT family; PFAM: extracellular solute-binding protein, family 3; KEGG: pai:PAE2096 bacterial extracellular solute-binding proteins, family 3; TC 3.A.1.3.-.
  
  
 0.624
Pars_0242
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE1131 flavoprotein reductase, conjectural.
  
 
 0.604
Pars_0912
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sso:SSO2629 oxidoreductase (flavoprotein).
  
 
 0.604
Pars_0922
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE2834 hypothetical protein.
  
 
 0.604
Pars_1218
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE2618 flavoprotein reductase, conjectural.
  
 
 0.604
Pars_1572
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: pai:PAE2371 NADH oxidase (nox).
  
 
 0.604
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.576
rps14
SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles.
       0.500
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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