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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pars_2012D-proline dehydrogenase; PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE2095 conserved within P.aerophilum. (365 aa)    
Predicted Functional Partners:
Pars_2117
PFAM: NADP oxidoreductase, coenzyme F420-dependent; KEGG: pai:PAE1917 pyrroline-5-carboxylate reductase.
  
 
 0.841
Pars_2013
PFAM: GCN5-related N-acetyltransferase; KEGG: sto:ST2612 hypothetical protein.
 
     0.816
Pars_2164
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE1841 hypothetical protein.
 
 
 0.724
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 
 0.634
Pars_2011
Amino acid ABC transporter substrate-binding protein, PAAT family; PFAM: extracellular solute-binding protein, family 3; KEGG: pai:PAE2096 bacterial extracellular solute-binding proteins, family 3; TC 3.A.1.3.-.
  
  
 0.608
Pars_0242
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE1131 flavoprotein reductase, conjectural.
  
 
 0.520
Pars_0912
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sso:SSO2629 oxidoreductase (flavoprotein).
  
 
 0.520
Pars_0922
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE2834 hypothetical protein.
  
 
 0.520
Pars_1218
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE2618 flavoprotein reductase, conjectural.
  
 
 0.520
Pars_1572
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: pai:PAE2371 NADH oxidase (nox).
  
 
 0.520
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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