STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pars_2015PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: pai:PAE2089 short chain dehydrogenase family. (243 aa)    
Predicted Functional Partners:
Pars_2207
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pai:PAE2832 short chain dehydrogenase.
  
  
 
0.919
Pars_0047
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pai:PAE0797 short chain dehydrogenase.
  
  
 
0.918
Pars_1239
PFAM: Ankyrin; KEGG: spu:580702 similar to ankyrin 2,3/unc44.
  
 0.693
Pars_0059
PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pai:PAE0815 serine/threonine protein kinase, putative.
  
 0.673
Pars_0984
PFAM: metallophosphoesterase; KEGG: pai:PAE2904 exonuclease SbcD, conjectural.
  
 
 0.606
Pars_2014
PFAM: Protein of unknown function DUF429; KEGG: pai:PAE2091 hypothetical protein.
       0.576
folD
Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
 
 0.487
Pars_0864
PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: pai:PAE2795 serine protease.
 
 
 0.482
Pars_1843
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: pai:PAE1650 enoyl-CoA hydratase, probable.
  
 0.468
Pars_1000
PFAM: NADH dehydrogenase (ubiquinone), 30 kDa subunit; KEGG: pai:PAE2926 NADH-ubiquinone oxidoreductase subunit.
   
 
 0.464
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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