Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pars_2115PFAM: PhoH family protein; KH, type 2 domain protein; KEGG: pai:PAE1920 PhoH like protein. (371 aa)    
Predicted Functional Partners:
Pars_2114
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pis:Pisl_1770 alcohol dehydrogenase GroES domain protein.
       0.701
Pars_2368
Molybdopterin synthase subunit MoaE / molybdopterin synthase subunit MoaD; TIGRFAM: MoaD family protein; PFAM: molybdopterin biosynthesis MoaE; thiamineS protein; KEGG: pai:PAE0727 molybdenum cofactor biosynthesis protein D/E.
       0.676
Pars_1655
PFAM: THUMP domain protein; KEGG: pai:PAE3175 hypothetical protein.
  
     0.637
Pars_2116
PFAM: NUDIX hydrolase; KEGG: pai:PAE1918 mutT/nudix family protein.
       0.570
fau-1
RNA-binding protein AU-1; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.
 
    0.517
Pars_0965
PFAM: extracellular solute-binding protein, family 5; KEGG: pai:PAE1300 dipeptide binding protein.
 
     0.486
Pars_0667
PFAM: protein of unknown function DUF6, transmembrane; KEGG: pai:PAE1545 hypothetical protein.
  
    0.469
Pars_0460
PFAM: protein of unknown function DUF6, transmembrane; KEGG: pai:PAE1372 hypothetical protein.
  
    0.467
Pars_0212
KEGG: pai:PAE1173 hypothetical protein.
  
     0.456
Pars_0181
PFAM: Polyprenyl synthetase; KEGG: pai:PAE1013 dimethylallyltranstransferase / geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
 
    0.442
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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