STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pars_2136PFAM: periplasmic binding protein; KEGG: pis:Pisl_1954 periplasmic binding protein. (442 aa)    
Predicted Functional Partners:
Pars_2137
PFAM: transport system permease protein; KEGG: pis:Pisl_1955 transport system permease protein.
 
     0.876
Pars_2138
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pis:Pisl_1956 ABC transporter related.
       0.789
cbiA
Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.570
Pars_1284
PFAM: transport system permease protein; KEGG: pis:Pisl_0215 transport system permease protein.
 
     0.433
Pars_1292
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: afu:AF1843 cobalamin biosynthesis protein.
  
  
 0.415
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
       0.409
Pars_1294
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pab:PAB2260 cobalt transport system ATP-binding protein.
  
  
 0.406
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.