Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pars_2159KEGG: pai:PAE0301 hypothetical protein. (189 aa)    
Predicted Functional Partners:
Pars_2158
PFAM: amidohydrolase; KEGG: pai:PAE0309 chlorohydrolase, conjectural.
       0.773
Pars_2160
KEGG: pai:PAE0297 hypothetical protein.
       0.566
Pars_2161
PFAM: HEPN domain protein; KEGG: pai:PAE0168 hypothetical protein.
       0.436
Pars_2162
PFAM: DNA polymerase, beta domain protein region; KEGG: pai:PAE0167 hypothetical protein.
       0.436
Your Current Organism:
Pyrobaculum arsenaticum
NCBI taxonomy Id: 340102
Other names: P. arsenaticum DSM 13514, Pyrobaculum arsenaticum DSM 13514, Pyrobaculum arsenaticum str. DSM 13514, Pyrobaculum arsenaticum strain DSM 13514
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