STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIQ43734.1Aromatic-amino-acid transaminase. (398 aa)    
Predicted Functional Partners:
SIQ75988.1
Chorismate mutase.
    
 0.951
SIP86965.1
Glutamate synthase (NADH) large subunit.
    
 0.927
SIQ76013.1
Prephenate dehydrogenase.
    
 0.920
SIP90252.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.916
hisC
Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
   
 
 0.912
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.908
SIQ82298.1
D-alanine transaminase.
     
 0.907
SIR61851.1
Aromatic-amino-acid transaminase.
  
  
 
0.902
ubiC
Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.
     
 0.900
katG
Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
 0.884
Your Current Organism:
Aromatoleum tolulyticum
NCBI taxonomy Id: 34027
Other names: A. tolulyticum, ATCC 51758, Azoarcus denitrificans, Azoarcus tolulyticus, CIP 109470, strain Tol-4
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