STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIR22931.1Putative membrane protein. (139 aa)    
Predicted Functional Partners:
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.951
hemF
Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
  
 0.944
SIQ28014.1
Oxygen-independent coproporphyrinogen-3 oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
  
 0.933
SIR22900.1
Nucleoside-diphosphate-sugar epimerase.
  
    0.812
SIR22955.1
Putative N6-adenine-specific DNA methylase; Belongs to the methyltransferase superfamily.
       0.660
SIR22827.1
CDP-4-dehydro-6-deoxyglucose reductase.
 
     0.657
SIP92014.1
Coproporphyrinogen III oxidase, anaerobic; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.595
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.572
SIR22798.1
EAL and modified HD-GYP domain-containing signal transduction protein.
       0.566
SIQ75273.1
Type 4 prepilin peptidase 1 Aspartic peptidase. MEROPS family A24A; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
   
    0.495
Your Current Organism:
Aromatoleum tolulyticum
NCBI taxonomy Id: 34027
Other names: A. tolulyticum, ATCC 51758, Azoarcus denitrificans, Azoarcus tolulyticus, CIP 109470, strain Tol-4
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