STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIR32709.1Fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (254 aa)    
Predicted Functional Partners:
SIR32727.1
Fumarate reductase subunit C.
 
 0.999
SIR32747.1
Succinate dehydrogenase subunit D; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane; Belongs to the FrdD family.
 
 0.999
SIR32685.1
Succinate dehydrogenase subunit A.
 0.997
SIP95823.1
NAD-dependent formate dehydrogenase flavoprotein subunit.
   
 0.993
SIQ24755.1
NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit.
   
 0.993
SIQ62731.1
Succinate dehydrogenase subunit C.
 
 0.989
SIQ62791.1
Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 0.989
SIQ10747.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.986
SIQ54205.1
Succinate dehydrogenase subunit C.
  
 0.982
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.981
Your Current Organism:
Aromatoleum tolulyticum
NCBI taxonomy Id: 34027
Other names: A. tolulyticum, ATCC 51758, Azoarcus denitrificans, Azoarcus tolulyticus, CIP 109470, strain Tol-4
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.