Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AOS60958.1Fumarylacetoacetate hydrolase. (401 aa)    
Predicted Functional Partners:
AOS60956.1
Homogentisate 1,2-dioxygenase.
 
  
 0.965
AOS61636.1
4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.886
fumC
Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
  0.820
AOS65665.1
Succinate dehydrogenase subunit A.
  
 
  0.814
AOS65666.1
Succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 
  0.809
AOS65664.1
Succinate dehydrogenase, hydrophobic anchor subunit.
   
 
  0.804
AOS65663.1
Succinate dehydrogenase subunit C.
   
 
  0.803
AOS60957.1
Hypothetical protein.
 
     0.783
AOS60959.1
Transcriptional regulator.
 
     0.776
AOS60960.1
Cytochrome bd-type quinol oxidase, subunit 1.
       0.490
Your Current Organism:
Actinoalloteichus hymeniacidonis
NCBI taxonomy Id: 340345
Other names: A. hymeniacidonis, Actinoalloteichus hymeniacidonis Zhang et al. 2006 emend. Nouioui et al. 2018, Actinomycetales bacterium HPA177, CGMCC 4.2500, DSM 45092, JCM 13436, strain HPA177
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