close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOS61328.1Cytochrome c biogenesis protein. (283 aa)    
Predicted Functional Partners:
AOS61330.1
Cytochrome c-type biogenesis protein CcsB.
 
  
 0.994
AOS61329.1
Cytochrome c biogenesis membrane protein.
 
  
 0.985
AOS61325.1
Thiol-disulfide isomerase-like thioredoxin.
 
  
 0.748
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
  
 0.725
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
     
 0.711
AOS65139.1
Heme/copper-type cytochrome/quinol oxidase, subunit 3.
  
   
 0.690
AOS62109.1
Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
  
   
 0.648
AOS61101.1
Thiol-disulfide isomerase-like thioredoxin.
 
  
 0.634
AOS61331.1
Hypothetical protein; ATPases involved in chromosome partitioning.
       0.593
AOS61316.1
uroporphyrinogen-III synthase.
  
    0.565
Your Current Organism:
Actinoalloteichus hymeniacidonis
NCBI taxonomy Id: 340345
Other names: A. hymeniacidonis, Actinoalloteichus hymeniacidonis Zhang et al. 2006 emend. Nouioui et al. 2018, Actinomycetales bacterium HPA177, CGMCC 4.2500, DSM 45092, JCM 13436, strain HPA177
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.