| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOS61094.1 | AOS61785.1 | TL08_01265 | TL08_04775 | NUDIX family protein. | Transcriptional regulator, TetR family. | 0.454 |
| AOS61785.1 | AOS61094.1 | TL08_04775 | TL08_01265 | Transcriptional regulator, TetR family. | NUDIX family protein. | 0.454 |
| AOS61785.1 | AOS63225.1 | TL08_04775 | TL08_12055 | Transcriptional regulator, TetR family. | Proteasome accessory factor PafA2. | 0.519 |
| AOS61785.1 | AOS65353.1 | TL08_04775 | TL08_22865 | Transcriptional regulator, TetR family. | Cobalamin-independent methionine synthase. | 0.628 |
| AOS61785.1 | AOS65366.1 | TL08_04775 | TL08_22930 | Transcriptional regulator, TetR family. | Transcriptional regulator, TetR family. | 0.404 |
| AOS61785.1 | arc | TL08_04775 | TL08_12040 | Transcriptional regulator, TetR family. | Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.405 |
| AOS61785.1 | pafA | TL08_04775 | TL08_12085 | Transcriptional regulator, TetR family. | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.526 |
| AOS63225.1 | AOS61785.1 | TL08_12055 | TL08_04775 | Proteasome accessory factor PafA2. | Transcriptional regulator, TetR family. | 0.519 |
| AOS63225.1 | arc | TL08_12055 | TL08_12040 | Proteasome accessory factor PafA2. | Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.876 |
| AOS65353.1 | AOS61785.1 | TL08_22865 | TL08_04775 | Cobalamin-independent methionine synthase. | Transcriptional regulator, TetR family. | 0.628 |
| AOS65366.1 | AOS61785.1 | TL08_22930 | TL08_04775 | Transcriptional regulator, TetR family. | Transcriptional regulator, TetR family. | 0.404 |
| arc | AOS61785.1 | TL08_12040 | TL08_04775 | Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Transcriptional regulator, TetR family. | 0.405 |
| arc | AOS63225.1 | TL08_12040 | TL08_12055 | Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Proteasome accessory factor PafA2. | 0.876 |
| arc | pafA | TL08_12040 | TL08_12085 | Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.902 |
| pafA | AOS61785.1 | TL08_12085 | TL08_04775 | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | Transcriptional regulator, TetR family. | 0.526 |
| pafA | arc | TL08_12085 | TL08_12040 | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.902 |
