STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOS62666.1uroporphyrinogen-III synthase. (376 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.978
AOS62635.1
uroporphyrin-III C-methyltransferase.
 
 
 0.975
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.961
AOS62668.1
NAD(P)H-dependent nitrite reductase, large subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.955
AOS61316.1
uroporphyrinogen-III synthase.
 
 
 0.946
AOS62667.1
NAD(P)H-dependent nitrite reductase, small subunit.
 
  
 0.945
AOS61792.1
uroporphyrinogen-III synthase.
  
  
0.908
AOS62669.1
Nitrate/nitrite transporter.
 
  
 0.904
AOS61317.1
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
 
 0.727
AOS62671.1
Molybdopterin dinucleotide binding protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
   
 0.710
Your Current Organism:
Actinoalloteichus hymeniacidonis
NCBI taxonomy Id: 340345
Other names: A. hymeniacidonis, Actinoalloteichus hymeniacidonis Zhang et al. 2006 emend. Nouioui et al. 2018, Actinomycetales bacterium HPA177, CGMCC 4.2500, DSM 45092, JCM 13436, strain HPA177
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.