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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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pfpPhosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa)    
Predicted Functional Partners:
AOS63152.1
Phosphoglucose isomerase; Belongs to the GPI family.
 
 0.983
AOS66008.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
 
 
 0.962
AOS61664.1
Fructose-1,6-bisphosphatase, class II.
  
 
 0.946
AOS64147.1
Ketose-bisphosphate aldolase.
 
 
 0.944
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
   
 0.934
AOS63154.1
Transketolase; Belongs to the transketolase family.
  
 0.932
AOS64372.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.923
AOS65448.1
Mannose-6-phosphate isomerase, type 1.
    
 0.916
AOS65800.1
Sugar kinase, ribokinase.
  
 0.914
AOS64652.1
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
     
 0.909
Your Current Organism:
Actinoalloteichus hymeniacidonis
NCBI taxonomy Id: 340345
Other names: A. hymeniacidonis, Actinoalloteichus hymeniacidonis Zhang et al. 2006 emend. Nouioui et al. 2018, Actinomycetales bacterium HPA177, CGMCC 4.2500, DSM 45092, JCM 13436, strain HPA177
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