Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AME00724.1Disulfide bond formation protein DsbE; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)    
Predicted Functional Partners:
ccmI
Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.971
AME00725.1
Cytochrome c-type biogenesis protein; required for the transfer of heme to apocytochrome c; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.965
AME02231.1
Cytochrome C biogenesis protein; Possible subunit of a heme lyase.
 
  
 0.963
msrB
Methionine sulfoxide reductase B; This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.923
AME02406.1
Trifunctional thioredoxin/methionine sulfoxide reductase A/B protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.923
ccmE
Cytochrome c biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
  
 0.920
ccmC
Heme ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
  
 0.910
AME00960.1
Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.908
AME01230.1
ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
  
 0.859
ccmA
Cytochrome c biogenesis ABC transporter ATP-binding protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
   
 0.757
Your Current Organism:
Moraxella osloensis
NCBI taxonomy Id: 34062
Other names: ATCC 19976, CCUG 350, CIP 68.35, DSM 6998, LMG 5131, LMG:5131, M. osloensis, NCTC 10465, strain A1920
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