STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureDHypothetical protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (317 aa)    
Predicted Functional Partners:
ureF
Hypothetical protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.997
ureA
Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family.
 
 
 0.947
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.939
ureE
Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.933
ureC
Urease subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease beta subunit family.
 
  
 0.772
urtC
Urea ABC transporter permease subunit UrtC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.
 
   
 0.584
AME01707.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
   
 0.582
urtA
Branched-chain amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.557
urtD
Urea ABC transporter ATP-binding protein UrtD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.550
urtB
Branched-chain amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.
 
   
 0.543
Your Current Organism:
Moraxella osloensis
NCBI taxonomy Id: 34062
Other names: ATCC 19976, CCUG 350, CIP 68.35, DSM 6998, LMG 5131, LMG:5131, M. osloensis, NCTC 10465, strain A1920
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