| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AME00436.1 | AME01573.1 | AXE82_00535 | AXE82_07235 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.888 |
| AME00436.1 | mutY | AXE82_00535 | AXE82_08150 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.893 |
| AME00436.1 | polA | AXE82_00535 | AXE82_08785 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.852 |
| AME01573.1 | AME00436.1 | AXE82_07235 | AXE82_00535 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.888 |
| AME01573.1 | AME02101.1 | AXE82_07235 | AXE82_10325 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA mismatch repair MutL/HexB family. | 0.954 |
| AME01573.1 | mutY | AXE82_07235 | AXE82_08150 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.862 |
| AME01573.1 | polA | AXE82_07235 | AXE82_08785 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.994 |
| AME01735.1 | mutY | AXE82_08155 | AXE82_08150 | Dienelactone hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.569 |
| AME02101.1 | AME01573.1 | AXE82_10325 | AXE82_07235 | DNA mismatch repair protein MutL; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA mismatch repair MutL/HexB family. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.954 |
| AME02101.1 | mutM | AXE82_10325 | AXE82_04590 | DNA mismatch repair protein MutL; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA mismatch repair MutL/HexB family. | 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.468 |
| AME02101.1 | mutY | AXE82_10325 | AXE82_08150 | DNA mismatch repair protein MutL; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA mismatch repair MutL/HexB family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.542 |
| AME02101.1 | polA | AXE82_10325 | AXE82_08785 | DNA mismatch repair protein MutL; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA mismatch repair MutL/HexB family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.955 |
| AME02101.1 | radA | AXE82_10325 | AXE82_10370 | DNA mismatch repair protein MutL; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA mismatch repair MutL/HexB family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.474 |
| AME02101.1 | ruvA | AXE82_10325 | AXE82_01015 | DNA mismatch repair protein MutL; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA mismatch repair MutL/HexB family. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.494 |
| AME02406.1 | msrB | AXE82_10750 | AXE82_05420 | Trifunctional thioredoxin/methionine sulfoxide reductase A/B protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine sulfoxide reductase B; This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
| AME02406.1 | mutM | AXE82_10750 | AXE82_04590 | Trifunctional thioredoxin/methionine sulfoxide reductase A/B protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.413 |
| AME02406.1 | mutY | AXE82_10750 | AXE82_08150 | Trifunctional thioredoxin/methionine sulfoxide reductase A/B protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.548 |
| AME02406.1 | polA | AXE82_10750 | AXE82_08785 | Trifunctional thioredoxin/methionine sulfoxide reductase A/B protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.682 |
| AME02406.1 | radA | AXE82_10750 | AXE82_10370 | Trifunctional thioredoxin/methionine sulfoxide reductase A/B protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.508 |
| AME02406.1 | ruvA | AXE82_10750 | AXE82_01015 | Trifunctional thioredoxin/methionine sulfoxide reductase A/B protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.458 |
