Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ahpCAlkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (188 aa)    
Predicted Functional Partners:
ahpF
Alkyl hydroperoxide reductase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.976
msrB
Methionine sulfoxide reductase B; This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.908
AME02406.1
Trifunctional thioredoxin/methionine sulfoxide reductase A/B protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.908
AME01548.1
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.889
trxB
Thioredoxin reductase; Catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.852
AME01538.1
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 
 0.723
AME01904.1
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family.
    
 
 0.716
AME00724.1
Disulfide bond formation protein DsbE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.669
AME01410.1
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.668
trxA
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
  
 
 0.656
Your Current Organism:
Moraxella osloensis
NCBI taxonomy Id: 34062
Other names: ATCC 19976, CCUG 350, CIP 68.35, DSM 6998, LMG 5131, LMG:5131, M. osloensis, NCTC 10465, strain A1920
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