Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cbsPutative cystathionine beta-synthase. (345 aa)    
Predicted Functional Partners:
metZ
O-succinylhomoserine sulfhydrylase.
 
 0.968
cysE-2
Serine acetyltransferase.
 
 0.958
cysE
Serine acetyltransferase.
 
 0.953
cysS
Cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.922
thrA
Bifunctional aspartokinase/homoserine dehydrogenase 1.
  
 
 0.911
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.890
cysK
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
  
 
0.882
metX
Homoserine O-acetyltransferase.
    
 0.880
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
   
 
 0.878
sdaA
L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.875
Your Current Organism:
Riemerella anatipestifer
NCBI taxonomy Id: 34085
Other names: ATCC 11845, CCUG 14215, CCUG 21370, CIP 82.28, DSM 15868, JCM 9532, LMG 11054, LMG 11606, LMG:11054, LMG:11606, MCCM 00568, Moraxella anatipestifer, NCTC 11014, Pasteurella anapestifer, Pasteurella anatipestifer, Pfeifferella anatipestifer, R. anatipestifer
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.