| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AB406_0127 | AB406_1253 | AB406_0127 | AB406_1253 | Hypothetical protein. | Hypothetical protein. | 0.415 |
| AB406_0127 | crp | AB406_0127 | AB406_0662 | Hypothetical protein. | cAMP-activated global transcriptional regulator CRP. | 0.422 |
| AB406_0736 | AB406_1253 | AB406_0736 | AB406_1253 | Hypothetical protein. | Hypothetical protein. | 0.501 |
| AB406_0736 | crp | AB406_0736 | AB406_0662 | Hypothetical protein. | cAMP-activated global transcriptional regulator CRP. | 0.501 |
| AB406_1253 | AB406_0127 | AB406_1253 | AB406_0127 | Hypothetical protein. | Hypothetical protein. | 0.415 |
| AB406_1253 | AB406_0736 | AB406_1253 | AB406_0736 | Hypothetical protein. | Hypothetical protein. | 0.501 |
| AB406_1253 | crp | AB406_1253 | AB406_0662 | Hypothetical protein. | cAMP-activated global transcriptional regulator CRP. | 0.764 |
| crp | AB406_0127 | AB406_0662 | AB406_0127 | cAMP-activated global transcriptional regulator CRP. | Hypothetical protein. | 0.422 |
| crp | AB406_0736 | AB406_0662 | AB406_0736 | cAMP-activated global transcriptional regulator CRP. | Hypothetical protein. | 0.501 |
| crp | AB406_1253 | AB406_0662 | AB406_1253 | cAMP-activated global transcriptional regulator CRP. | Hypothetical protein. | 0.764 |
| crp | folD | AB406_0662 | AB406_0661 | cAMP-activated global transcriptional regulator CRP. | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.773 |
| crp | glyA | AB406_0662 | AB406_0659 | cAMP-activated global transcriptional regulator CRP. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.471 |
| crp | hchA | AB406_0662 | AB406_0663 | cAMP-activated global transcriptional regulator CRP. | Molecular chaperone Hsp31 and glyoxalase 3. | 0.538 |
| crp | pgi | AB406_0662 | AB406_0660 | cAMP-activated global transcriptional regulator CRP. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.653 |
| folD | crp | AB406_0661 | AB406_0662 | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | cAMP-activated global transcriptional regulator CRP. | 0.773 |
| folD | glyA | AB406_0661 | AB406_0659 | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.985 |
| folD | hchA | AB406_0661 | AB406_0663 | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Molecular chaperone Hsp31 and glyoxalase 3. | 0.488 |
| folD | pgi | AB406_0661 | AB406_0660 | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.727 |
| glyA | crp | AB406_0659 | AB406_0662 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | cAMP-activated global transcriptional regulator CRP. | 0.471 |
| glyA | folD | AB406_0659 | AB406_0661 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.985 |