| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cobB | nadD | AB406_2230 | AB406_0769 | NAD-dependent protein deacylase; Belongs to the sirtuin family. Class III subfamily. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.927 |
| cobB | nadE | AB406_2230 | AB406_1530 | NAD-dependent protein deacylase; Belongs to the sirtuin family. Class III subfamily. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.923 |
| cobB | pncC | AB406_2230 | AB406_0323 | NAD-dependent protein deacylase; Belongs to the sirtuin family. Class III subfamily. | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | 0.453 |
| cobB | ppnK | AB406_2230 | AB406_0815 | NAD-dependent protein deacylase; Belongs to the sirtuin family. Class III subfamily. | Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.919 |
| gmk | nadD | AB406_1429 | AB406_0769 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.833 |
| nadD | cobB | AB406_0769 | AB406_2230 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD-dependent protein deacylase; Belongs to the sirtuin family. Class III subfamily. | 0.927 |
| nadD | gmk | AB406_0769 | AB406_1429 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.833 |
| nadD | nadE | AB406_0769 | AB406_1530 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.932 |
| nadD | pncB2 | AB406_0769 | AB406_1278 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinate phosphoribosyltransferase 2; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.931 |
| nadD | pncC | AB406_0769 | AB406_0323 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | 0.967 |
| nadD | ppnK | AB406_0769 | AB406_0815 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.939 |
| nadD | rsfS | AB406_0769 | AB406_1126 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.792 |
| nadD | surE | AB406_0769 | AB406_1070 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
| nadD | yfkN | AB406_0769 | AB406_1703 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Trifunctional nucleotide phosphoesterase protein YfkN precursor. | 0.900 |
| nadD | yfkN-2 | AB406_0769 | AB406_1704 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family. | 0.900 |
| nadE | cobB | AB406_1530 | AB406_2230 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | NAD-dependent protein deacylase; Belongs to the sirtuin family. Class III subfamily. | 0.923 |
| nadE | nadD | AB406_1530 | AB406_0769 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.932 |
| nadE | pncB2 | AB406_1530 | AB406_1278 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Nicotinate phosphoribosyltransferase 2; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.539 |
| nadE | pncC | AB406_1530 | AB406_0323 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. | 0.582 |
| nadE | ppnK | AB406_1530 | AB406_0815 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.929 |