STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdkThymidine kinase. (195 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.962
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
  
 0.932
ribD
Riboflavin biosynthesis protein RibD.
  
 
 0.929
udp
Uridine phosphorylase.
     
 0.915
yfkN
Trifunctional nucleotide phosphoesterase protein YfkN precursor.
 
  
  0.912
punA
Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
  0.907
yfkN-2
Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family.
    
  0.901
surE
5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
    0.836
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
  
 0.746
Your Current Organism:
Riemerella anatipestifer
NCBI taxonomy Id: 34085
Other names: ATCC 11845, CCUG 14215, CCUG 21370, CIP 82.28, DSM 15868, JCM 9532, LMG 11054, LMG 11606, LMG:11054, LMG:11606, MCCM 00568, Moraxella anatipestifer, NCTC 11014, Pasteurella anapestifer, Pasteurella anatipestifer, Pfeifferella anatipestifer, R. anatipestifer
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