| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AB406_0325 | cbs | AB406_0325 | AB406_0237 | Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Putative cystathionine beta-synthase. | 0.900 |
| AB406_0325 | glyA | AB406_0325 | AB406_0659 | Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
| AB406_0325 | sdaA | AB406_0325 | AB406_1599 | Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.900 |
| AB406_0325 | trpA | AB406_0325 | AB406_1978 | Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase alpha chain. | 0.900 |
| AB406_0325 | trpB | AB406_0325 | AB406_1977 | Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| cbs | AB406_0325 | AB406_0237 | AB406_0325 | Putative cystathionine beta-synthase. | Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| cbs | glyA | AB406_0237 | AB406_0659 | Putative cystathionine beta-synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.923 |
| cbs | sdaA | AB406_0237 | AB406_1599 | Putative cystathionine beta-synthase. | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.906 |
| cbs | trpA | AB406_0237 | AB406_1978 | Putative cystathionine beta-synthase. | Tryptophan synthase alpha chain. | 0.910 |
| cbs | trpB | AB406_0237 | AB406_1977 | Putative cystathionine beta-synthase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.905 |
| glyA | AB406_0325 | AB406_0659 | AB406_0325 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| glyA | cbs | AB406_0659 | AB406_0237 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative cystathionine beta-synthase. | 0.923 |
| glyA | sdaA | AB406_0659 | AB406_1599 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.956 |
| glyA | trpA | AB406_0659 | AB406_1978 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase alpha chain. | 0.928 |
| glyA | trpB | AB406_0659 | AB406_1977 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.922 |
| pabA | trpA | AB406_1972 | AB406_1978 | Aminodeoxychorismate synthase component 2. | Tryptophan synthase alpha chain. | 0.964 |
| pabA | trpB | AB406_1972 | AB406_1977 | Aminodeoxychorismate synthase component 2. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.963 |
| pabA | trpC | AB406_1972 | AB406_1975 | Aminodeoxychorismate synthase component 2. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.998 |
| pabA | trpE | AB406_1972 | AB406_1971 | Aminodeoxychorismate synthase component 2. | Anthranilate synthase component 1. | 0.999 |
| pabA | trpF | AB406_1972 | AB406_1976 | Aminodeoxychorismate synthase component 2. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.982 |