STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDL48934.1ATP-dependent DNA helicase RecQ. (630 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.987
sbcD
Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 0.968
recA
Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.956
SDL80342.1
DNA topoisomerase-3.
 
 
 0.954
SDL67237.1
DNA helicase-2 / ATP-dependent DNA helicase PcrA.
 
 0.945
SDM45802.1
DNA topoisomerase-3.
 
 
 0.937
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.921
SDM04505.1
ATP-dependent RNA helicase DeaD; Belongs to the DEAD box helicase family.
  
 
0.920
SDM82878.1
C-terminal repeat of topoisomerase.
   
 0.910
SDL80980.1
ATP-dependent DNA helicase RecQ.
  
  
 
0.906
Your Current Organism:
Pedobacter antarcticus
NCBI taxonomy Id: 34086
Other names: ATCC 51969, CIP 104195 [[Pedobacter piscium]], DSM 11725 [[Pedobacter piscium]], IFO 14985 [[Pedobacter piscium]], JCM 7454 [[Pedobacter piscium]], KCTC 12489 [[Pedobacter piscium]], LMG 14024 [[Pedobacter piscium]], LMG:14024 [[Pedobacter piscium]], MTCC 675, NBRC 14985 [[Pedobacter piscium]], NCIMB 13704 [[Pedobacter piscium]], P. antarcticus, Pedobacter piscium, Sphingobacterium antarcticum, Sphingobacterium antarcticus, Sphingobacterium piscium, strain 4BY
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