STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDM39171.1Glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (241 aa)    
Predicted Functional Partners:
SDM39102.1
Glycerol-3-phosphate dehydrogenase.
  
 0.959
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 
 
 0.953
SDL77332.1
Serine/threonine protein phosphatase PrpC.
    
   0.837
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
 0.746
SDM39200.1
Hypothetical protein.
       0.693
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
   
  
 0.653
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
    
 
 0.555
SDM39069.1
Uncharacterized domain 1-containing protein.
       0.538
SDL75483.1
Peptidyl-prolyl cis-trans isomerase B (cyclophilin B).
    
   0.528
SDM04212.1
Peptidyl-prolyl cis-trans isomerase B (cyclophilin B); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.528
Your Current Organism:
Pedobacter antarcticus
NCBI taxonomy Id: 34086
Other names: ATCC 51969, CIP 104195 [[Pedobacter piscium]], DSM 11725 [[Pedobacter piscium]], IFO 14985 [[Pedobacter piscium]], JCM 7454 [[Pedobacter piscium]], KCTC 12489 [[Pedobacter piscium]], LMG 14024 [[Pedobacter piscium]], LMG:14024 [[Pedobacter piscium]], MTCC 675, NBRC 14985 [[Pedobacter piscium]], NCIMB 13704 [[Pedobacter piscium]], P. antarcticus, Pedobacter piscium, Sphingobacterium antarcticum, Sphingobacterium antarcticus, Sphingobacterium piscium, strain 4BY
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.