STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nthDNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (224 aa)    
Predicted Functional Partners:
SFB78858.1
Exodeoxyribonuclease-3.
 
 0.998
rnfE
Electron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
 
  
 0.849
SFB69647.1
ComEC/Rec2-related protein.
       0.817
SFB69671.1
Diguanylate cyclase, GGDEF domain.
       0.790
SFB67323.1
A/G-specific DNA-adenine glycosylase.
 
 
0.776
SFB69607.1
Alcohol dehydrogenase, class IV.
       0.768
SFB69627.1
Hypothetical protein.
       0.768
SFB69597.1
Protein of unknown function.
       0.707
SFB69579.1
Tetratricopeptide repeat-containing protein.
       0.688
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.686
Your Current Organism:
Brevinema andersonii
NCBI taxonomy Id: 34097
Other names: ATCC 43811, B. andersonii, strain CT11616
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.